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Therefore, the RNA transport function of extracellular vesicles in sperm plays an important role in establishing sperm epigenome, which then affects embryonic development and ultimately leads to the transgenerational transmission of epigenetic effects by environmental effects (Ashapkin et al., 2023)

Over the 20th century, additional treatments were developed and FDA approved for treatment of overweight and obesity, including phentermine, phentermine/topiramate, orlistat, and naltrexone/bupropion